A Review of Hemodynamic Parameters in Cerebral Aneurysm

A cerebral aneurysm is a localized enlargement of a blood vessel in the brain caused by a weakened vessel wall. It typically appears as a bulge, balloon-like structure, or a small blister. Gaining insight into the mechanisms underlying the formation, growth, and rupture of cerebral aneurysms is crucial for devising treatments to mitigate the risks of mortality and severe complications. These aneurysms arise due to the thinning of arterial walls and are often difficult to detect until they rupture, leading to potentially life-threatening conditions such as hemorrhagic stroke, brain injury, visual impairments, and changes in behavior. Computational fluid dynamics (CFD) has proven valuable in studying cerebral aneurysms by modeling blood flow and analyzing hemodynamic parameters. These parameters play a critical role in assessing rupture risks and influencing biological processes within the affected vessels. This review examines the relationship between key hemodynamic factors and the formation, progression, and rupture of cerebral aneurysms. Additionally, it highlights how these factors are associated with the aneurysm's size, shape, and other morphological characteristics, shedding light on their significance in understanding aneurysm behavior.