Bipyramidal Gold Nanoparticles-Assisted Plasmonic Photothermal Therapy for Ocular Applications

The present dataset includes the complete experimental characterization of the ligand-capped bipyramidal gold nanoparticles, using the following techniques: UV-vis, FTIR, XPS, and TEM (Figures 1-4). Data from biological tests include viability quantitative results from in vitro biocompatibility studies of BipyAu@Citrate NPs using three different types of corneal cells and inverted fluorescence microscope images (Figure 5). Ex vivo experiments are included, with the following data: histology and cytotoxicity analysis of porcine corneas treated with PPTT (Figure 6), corneal curvature radius, sphericity and corneal distances evaluation of the porcine eyes (Figures 7 and 8). TEM images of the porcine cornea after PPTT treatment (Figure 9).