DAMAGE TO THE HISTOLOGICAL TISSUES OF THE RESPIRATORY TRACT IN CHILDREN DUE TO THE ENVIRONMENTAL POLLUTION

Environmental pollution poses a significant threat to respiratory health, impacting the delicate histological tissues within the respiratory tract. This study examines the effects of airborne pollutants—including particulate matter (PM), volatile organic compounds (VOCs), and nitrogen oxides (NOx)—on the epithelial and submucosal layers of the respiratory system. Histological analysis of exposed respiratory tissue reveals structural changes, including epithelial cell apoptosis, thickening of the basal membrane, and degradation of ciliary function, all of which compromise the respiratory tract’s defense mechanisms. Pollutant-induced oxidative stress and inflammation appear to play critical roles in tissue damage, leading to impaired mucociliary clearance and increased vulnerability to respiratory infections and chronic conditions such as asthma and chronic obstructive pulmonary disease (COPD). These findings underscore the importance of addressing air quality standards and adopting preventive measures to reduce pollutant exposure and mitigate its effects on respiratory tissue integrity.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-11-19
DOI
https://doi.org/10.5281/zenodo.14185422
Primary Topic
Air Quality and Health Impacts
Type
article
Field-Weighted Citation Impact
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article

DAMAGE TO THE HISTOLOGICAL TISSUES OF THE RESPIRATORY TRACT IN CHILDREN DUE TO THE ENVIRONMENTAL POLLUTION

Zenodo (CERN European Organization for Nuclear Research)
Air Quality and Health Impacts
article

DAMAGE TO THE HISTOLOGICAL TISSUES OF THE RESPIRATORY TRACT IN CHILDREN DUE TO THE ENVIRONMENTAL POLLUTION

article en

Abstract

Environmental pollution poses a significant threat to respiratory health, impacting the delicate histological tissues within the respiratory tract. This study examines the effects of airborne pollutants—including particulate matter (PM), volatile organic compounds (VOCs), and nitrogen oxides (NOx)—on the epithelial and submucosal layers of the respiratory system. Histological analysis of exposed respiratory tissue reveals structural changes, including epithelial cell apoptosis, thickening of the basal membrane, and degradation of ciliary function, all of which compromise the respiratory tract’s defense mechanisms. Pollutant-induced oxidative stress and inflammation appear to play critical roles in tissue damage, leading to impaired mucociliary clearance and increased vulnerability to respiratory infections and chronic conditions such as asthma and chronic obstructive pulmonary disease (COPD). These findings underscore the importance of addressing air quality standards and adopting preventive measures to reduce pollutant exposure and mitigate its effects on respiratory tissue integrity.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 58%
Air Quality and Health Impacts
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