Correlating Colonic Mucosal Alterations with Severity of Portal Hypertension in Liver Cirrhosis Patients: A Histopathological and Clinical Study

Background: The aim of the study is to find relationship between Colonic Mucosal changes in patients of Liver Cirrhosis with Portal Hypertension conducted at JNKTMCH, Madhepura. Result: The commonest symptom in patients was abdominal distension 30 (100%), next common was jaundice 20 (66.7%), malena 17 (56.7%), hemetemesis 10(33.3%), hematochezia 10(33.3%), and pruritis 2(6.6%) was noted. It is evident from table no.13 that out of 30 patients, serum prothrombin time was prolonged in 30 (100%) patients, serum albumin was decreased in 20 (66.7%) patients, platelet count was decreased in 16 (53.3%), serum bilirubin was raised in 14 (46.7%) patients, SGOT/SGPT was raised in 17 (56.7%) patients. Conclusion: Our study states that most of the changes which we found on colonoscopic studies were similar to other studies. The only finding which we got in excess in comparison to other studies was colitis like abnormality which was 73.3% which may be probably due to chronic intestinal infections which occur in our country.