Quality Control Assessment on Comparative Study of Different Marketed Brands of Cetirizine Hydrochlorde Tablet

Background –Cetirizine Hydrochloride has become a widely used option for managing allergic symptoms effectively and safely.Aim –The Objective of the study is to perfume a thorough quality control evaluation of various brands of Cetirizine Hydrochloride tablets that are currently available in the market.Methodology- The research approach entails the gathering of samples from pharmacies, succeeded by a physicochemical analysis that encompasses assessments of weight uniformity, hardness, friability, disintegration time, and dissolution profile. Result – The research indicated that all products complied with pharmacopoeial standards and exhibited similar dissolution profiles; however, a notable price disparity was also observed.Conclusion –All productions complied with the established requirements and fell within the pharmacopoeial limits for the tests conducted. The reference product of cetirizine continues to perform strongly in the open pharmaceutical market, despite its higher cost and the availability of other generics that possess nearly identical qualities.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-04-02
DOI
https://doi.org/10.5281/zenodo.15127245
Primary Topic
Analytical Methods in Pharmaceuticals
Type
article
Field-Weighted Citation Impact
0.00
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article

Quality Control Assessment on Comparative Study of Different Marketed Brands of Cetirizine Hydrochlorde Tablet

Zenodo (CERN European Organization for Nuclear Research)
Analytical Methods in Pharmaceuticals
article

Quality Control Assessment on Comparative Study of Different Marketed Brands of Cetirizine Hydrochlorde Tablet

article en

Abstract

Background –Cetirizine Hydrochloride has become a widely used option for managing allergic symptoms effectively and safely.Aim –The Objective of the study is to perfume a thorough quality control evaluation of various brands of Cetirizine Hydrochloride tablets that are currently available in the market.Methodology- The research approach entails the gathering of samples from pharmacies, succeeded by a physicochemical analysis that encompasses assessments of weight uniformity, hardness, friability, disintegration time, and dissolution profile. Result – The research indicated that all products complied with pharmacopoeial standards and exhibited similar dissolution profiles; however, a notable price disparity was also observed.Conclusion –All productions complied with the established requirements and fell within the pharmacopoeial limits for the tests conducted. The reference product of cetirizine continues to perform strongly in the open pharmaceutical market, despite its higher cost and the availability of other generics that possess nearly identical qualities.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 56%
Analytical Methods in Pharmaceuticals
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Quality Control Assessment on Comparative Study of Different Marketed Brands of Cetirizine Hydrochlorde Tablet · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS