Impact of Wuzi Yanzong (WZYZ) Formula on Semen Quality in Men with Sub-optimal Parameters: A Double-Blinded, Placebo-Controlled, Randomized Trial

This dataset contains data from a double-blinded, randomized, placebo-controlled clinical trial conducted at a large teaching hospital in Hong Kong. The study aimed to evaluate the effects of Wuzi Yanzong (WZYZ) formula, a Traditional Chinese Medicine, on semen quality, sperm function, and reproductive outcomes in men with suboptimal semen parameters, as defined by WHO (5th edition) criteria. Study Design: • Study Period: February 2018 – December 2022 • Sample Size: 153 men with suboptimal semen parameters • Randomization: Treatment group (WZYZ formula) vs. Placebo group • Intervention: WZYZ formula or placebo, taken twice daily for 12 weeks • Follow-up: • Semen analysis at baseline, 6 weeks, 3 months, and 6 months