Cerimetric Estimation Of Terazosin Hydrochloride In Bulk Drugs And In Pharmaceutical Formulations

A simple, accurate and precise method was described for the determination of terazosin hydrochloride with cerium(IV) sulphate. The method is based on the oxidation of the terazosin hydrochloride by a known excess amount of cerium(IV) sulphate in acid medium and the unreacted cerium(IV) sulphate is treated with iron(II) sulphate, and the iron(III) sulphate produced is complexed with thiocyanate and measured at 480 nm, thereby permitting the determination of the amount of unreacted cerium(IV) sulphate.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-08-20
DOI
https://doi.org/10.5281/zenodo.13351200
Primary Topic
Analytical Methods in Pharmaceuticals
Type
article
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article

Cerimetric Estimation Of Terazosin Hydrochloride In Bulk Drugs And In Pharmaceutical Formulations

Zenodo (CERN European Organization for Nuclear Research)
Analytical Methods in Pharmaceuticals
article

Cerimetric Estimation Of Terazosin Hydrochloride In Bulk Drugs And In Pharmaceutical Formulations

article en

Abstract

A simple, accurate and precise method was described for the determination of terazosin hydrochloride with cerium(IV) sulphate. The method is based on the oxidation of the terazosin hydrochloride by a known excess amount of cerium(IV) sulphate in acid medium and the unreacted cerium(IV) sulphate is treated with iron(II) sulphate, and the iron(III) sulphate produced is complexed with thiocyanate and measured at 480 nm, thereby permitting the determination of the amount of unreacted cerium(IV) sulphate.

Zenodo (CERN European Organization for Nuclear Research)
Clean water and sanitation
Openalex Percentile: Top 70%
Analytical Methods in Pharmaceuticals
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Cerimetric Estimation Of Terazosin Hydrochloride In Bulk Drugs And In Pharmaceutical Formulations · Zenodo (CERN European Organization for Nuclear Research) (2024) | TGRS Research Map | TGRS