Review of Chronic Kidney Disease in Older Adults: Pathophysiology, Reciprocal Relationship with Cardiovascular Disease, and Clinical Implications

Abstract: The prevalence of chronic kidney disease (CKD) is increasingly high among older adults. This study explores the intricate associations between CKD, aging and cardiovascular disease (CVD). The decline in renal function is due to several age-related changes such as the loss of muscle mass, stiffening blood vessels and impaired immune activity. For elderly individuals, genetic, lifestyle and age-related factors all play a part in having CKD. High blood pressure, diabetes, obesity and smoking are key causes of heart diseases and vascular damage that accelerate kidney injury. This review shows the relationship between CVD and CKD with focus on vascular aging as its main link. This vicious cycle worsens both diseases. It also highlights challenges in diagnosing and managing CKD among older persons which will require more research for improved prevention measures and management strategies. To improve the health outcomes of patients suffering from this disease, especially for old, aged people requires deep understanding of these aspects and eventually their quality of life should be enhanced. Keywords: chronic kidney disease, vascular system, cardiovascular disease, aging, elderly. Title: Review of Chronic Kidney Disease in Older Adults: Pathophysiology, Reciprocal Relationship with Cardiovascular Disease, and Clinical Implications Author: Shinnattapol Songpholratchanon, Pune Phetra, Jintapong Zuercher Thammachai, Kittanath Limphotong, Chananchida Dussadeethommo, Yadasiri Rachatasitikul International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Vol. 12, Issue 1, April 2024 - September 2024 Page No: 94-106 Research Publish Journals Website: www.researchpublish.com Published Date: 20-August-2024 DOI: https://doi.org/10.5281/zenodo.13348038 Paper Download Link (Source) https://www.researchpublish.com/papers/review-of-chronic-kidney-disease-in-older-adults-pathophysiology-reciprocal-relationship-with-cardiovascular-disease-and-clinical-implications