A Cross-Sectional Evaluation of Serum Calcium, Magnesium in Hypothyroid Subjects in Rohilkhand Region of Western Uttar Pradesh

Background: Thyroid hormones have a very significant role in the metabolic processes that occur in the human body. Hypothyroidism is the commonest form of thyroid dysfunction. Mineral metabolism is frequently disturbed in thyroid dysfunction. Aim: To evaluate the Serum calcium, magnesium in the newly diagnosed cases of hypothyroidism as compared to the euthyroid subjects. Methods: The present study was conducted 60 cases and 60 healthy subjects who attended the OPD of Rohilkhand Medical college and Hospital, Bareilly. The serum calcium levels were done by Ortho-cresolphthalein complexone method and serum Magnesium was assessed by calmagite method. Data was analyzed statistically using SPSS software. Result: We found decreased levels of serum calcium and increased levels of serum magnesium in hypothyroidism patients as compared to the euthyroid subjects. Our study shows statistically insignificant positive correlation of serum magnesium with TSH and there is no correlation between serum TSH and serum magnesium was observed in hypothyroid cases as compared to the controls. Conclusion: Our study found that serum Calcium levels are lower and serum Magnesium are higher in hypothyroid cases when compared to healthy subjects. A strong negative correlation between serum TSH levels and serum calcium was observed among hypothyroid individuals.