RESEARCH ON FORMULATION AND EVALUATION OF IN-SITU GEL OF MINOXIDIL

Abstract The research focuses on the formulation and evaluation of in-situ gel of minoxidil Androgenic alopecia (AGA) significantly affects both physical appearance and psychological well-being, leading to progressive hair thinning due to genetic and hormonal factors. Minoxidil, an FDA-approved treatment, has long been a cornerstone for addressing AGA. Originally developed for hypertension, it was repurposed after its hair growth-promoting effects were discovered. Despite its effectiveness, conventional minoxidil formulations require frequent applications and can cause scalp irritation, limiting their overall eficacy and patient adherence.