Monocytes but not plasmacytoid dendritic cells show aberrant TLR8 signaling in patients with systemic sclerosis (SSc)
Introduction: Systemic sclerosis (SSc) is a severe rheumatic disease, leading to inflammation and fibrotic tissue rearrangement of different organs like skin, lung, and heart. Increased type I interferon (IFN-I) signaling in blood and affected tissue was shown to mediate inflammation in SSc. Accordingly, [for full text, please go to the a.m. URL]
Institutions
- Medizinische Hochschule Hannover (DE)
- German Center for Lung Research (DE)
- Centre for Individualised Infection Medicine (DE)
- Center for Experimental and Clinical Infection Research (DE)
Publication Details
- Journal
- German Medical Science (German Research Foundation)
- Published
- 2024-09-18
- DOI
- https://doi.org/10.3205/24dgrh016
- Primary Topic
- Systemic Sclerosis and Related Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00