Expression and therapeutic potential of TROP-2 in Cisplatin-resistant non-seminomatous germ cell tumors

Background: Cisplatin-based chemotherapy has been the standard of care for metastatic germ cell tumors (mGCT) for the past four decades due to its high efficacy. However, cisplatin-refractory patients have a poor prognosis due to limited treatment options. Therefore, there is an unmet need for effective [for full text, please go to the a.m. URL]

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Publication Details

Journal
German Medical Science (German Research Foundation)
Published
2025-04-02
DOI
https://doi.org/10.3205/25nrwgu24
Primary Topic
Testicular diseases and treatments
Type
article
Field-Weighted Citation Impact
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article

Expression and therapeutic potential of TROP-2 in Cisplatin-resistant non-seminomatous germ cell tumors

German Medical Science (German Research Foundation)
Testicular diseases and treatments
article

Expression and therapeutic potential of TROP-2 in Cisplatin-resistant non-seminomatous germ cell tumors

article en

Abstract

Background: Cisplatin-based chemotherapy has been the standard of care for metastatic germ cell tumors (mGCT) for the past four decades due to its high efficacy. However, cisplatin-refractory patients have a poor prognosis due to limited treatment options. Therefore, there is an unmet need for effective [for full text, please go to the a.m. URL]

German Medical Science (German Research Foundation)
University Hospital Bonn (DE), Klinik und Poliklinik für Urologie (DE), Universitätsklinikum Erlangen (DE), Institut für Innovative Technologien (Germany) (DE), Centrum für Integrierte Onkologie (DE), University Hospital Cologne (DE), Bundeswehrzentralkrankenhaus Koblenz (DE)
No poverty
Openalex Percentile: Top 39%
Testicular diseases and treatments
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