The mechanism and targeted therapy of zinc mediating retinal ganglion cell injury through histone H4 deacetylation

Objective: Mammalian optic nerve cannot regenerate once injured. Our previous study found that mobile zinc (Zn2+) increased rapidly after optic nerve injury and it comes from amacrine cell (AC). Whether chelating Zn2+ or specifically knocked out zinc transporter 3 (ZnT3) in ACs significantly [for full text, please go to the a.m. URL]

Institutions

Publication Details

Journal
German Medical Science (German Research Foundation)
Published
2025-05-09
DOI
https://doi.org/10.3205/24artvis09
Primary Topic
Spam and Phishing Detection
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

The mechanism and targeted therapy of zinc mediating retinal ganglion cell injury through histone H4 deacetylation

German Medical Science (German Research Foundation)
Spam and Phishing Detection
article

The mechanism and targeted therapy of zinc mediating retinal ganglion cell injury through histone H4 deacetylation

article en

Abstract

Objective: Mammalian optic nerve cannot regenerate once injured. Our previous study found that mobile zinc (Zn2+) increased rapidly after optic nerve injury and it comes from amacrine cell (AC). Whether chelating Zn2+ or specifically knocked out zinc transporter 3 (ZnT3) in ACs significantly [for full text, please go to the a.m. URL]

German Medical Science (German Research Foundation)
Sun Yat-sen University (CN)
Good health and well-being
Openalex Percentile: Top 46%
Spam and Phishing Detection
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

The mechanism and targeted therapy of zinc mediating retinal ganglion cell injury through histone H4 deacetylation · German Medical Science (German Research Foundation) (2025) | TGRS Research Map | TGRS