eccDNA as aging markers In MSCs and released by extracellular vesicles

In this study, we specifically focused on the entire dynamics of eccDNA (extrachromosomal circular DNA) in intracellular, conditioned culture medium and extracellular vesicles(EVs) during stem cell senescence by culturing the umbilical cord mesenchymal stem cells in vitro, aiming to discover the characteristics of eccDNA changes in stem cells and the biological roles associated with senescence.

Publication Details

Journal
China National GeneBank DataBase
Published
2025-01-01
DOI
https://doi.org/10.26036/cnp0004523
Primary Topic
Extracellular vesicles in disease
Type
article
Field-Weighted Citation Impact
0.00
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article

eccDNA as aging markers In MSCs and released by extracellular vesicles

China National GeneBank DataBase
Extracellular vesicles in disease
article

eccDNA as aging markers In MSCs and released by extracellular vesicles

article en

Abstract

In this study, we specifically focused on the entire dynamics of eccDNA (extrachromosomal circular DNA) in intracellular, conditioned culture medium and extracellular vesicles(EVs) during stem cell senescence by culturing the umbilical cord mesenchymal stem cells in vitro, aiming to discover the characteristics of eccDNA changes in stem cells and the biological roles associated with senescence.

China National GeneBank DataBase
Openalex Percentile: Top 62%
Extracellular vesicles in disease
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eccDNA as aging markers In MSCs and released by extracellular vesicles · China National GeneBank DataBase (2025) | TGRS Research Map | TGRS