Intervention assessment tool for primary tumors in the liver

After a liver tumor intervention the medical doctor has to compare both pre and postoperative CT acquisitions to ensure that all carcinogenic cells are destroyed. A correct assessment of the intervention is of vital importance, since it will reduce the probability of tumor recurrence. Some methods have been proposed to support the medical doctors during the assessment process, however, all of them focus on secondary tumors. In this paper a tool is presented that enables the outcome validation for both primary and secondary tumors. Therefore, a multiphase registration (preoperative arterial and portal phases) followed by a registration between the pre and postoperative CT images is carried out. The first registration is in charge of the primary tumors that are only visible in the arterial phase. The secondary tumors will be incorporated in the second registration step. Finally, the part of the tumor that was not covered by the necrosis is quantified and visualized. The method has been tested in 9 patients, with an average registration error of 1.41 mm.

Publication Details

Journal
TUbilio (Technical University of Darmstadt)
Published
2025-01-01
DOI
https://doi.org/10.26083/tuprints-00029456
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
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article

Intervention assessment tool for primary tumors in the liver

TUbilio (Technical University of Darmstadt)
Hepatocellular Carcinoma Treatment and Prognosis
article

Intervention assessment tool for primary tumors in the liver

article en

Abstract

After a liver tumor intervention the medical doctor has to compare both pre and postoperative CT acquisitions to ensure that all carcinogenic cells are destroyed. A correct assessment of the intervention is of vital importance, since it will reduce the probability of tumor recurrence. Some methods have been proposed to support the medical doctors during the assessment process, however, all of them focus on secondary tumors. In this paper a tool is presented that enables the outcome validation for both primary and secondary tumors. Therefore, a multiphase registration (preoperative arterial and portal phases) followed by a registration between the pre and postoperative CT images is carried out. The first registration is in charge of the primary tumors that are only visible in the arterial phase. The secondary tumors will be incorporated in the second registration step. Finally, the part of the tumor that was not covered by the necrosis is quantified and visualized. The method has been tested in 9 patients, with an average registration error of 1.41 mm.

TUbilio (Technical University of Darmstadt)
Good health and well-being
Openalex Percentile: Top 45%
Hepatocellular Carcinoma Treatment and Prognosis
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Intervention assessment tool for primary tumors in the liver · TUbilio (Technical University of Darmstadt) (2025) | TGRS Research Map | TGRS