The Mediating Role of White Matter Hyperintensities in the Association Between Vascular Risk and Depressive Symptoms: A Causal Mediation Analysis of the ADNI Cohort

This study aims to determine whether cerebral white matter hyperintensities (a marker of cerebral small vessel disease) mediate the relationship between cumulative vascular risk and the severity of depressive symptoms in an older adult population.

Publication Details

Journal
Open Science Framework
Published
2025-01-01
DOI
https://doi.org/10.17605/osf.io/z9rce
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

The Mediating Role of White Matter Hyperintensities in the Association Between Vascular Risk and Depressive Symptoms: A Causal Mediation Analysis of the ADNI Cohort

Open Science Framework
Dementia and Cognitive Impairment Research
article

The Mediating Role of White Matter Hyperintensities in the Association Between Vascular Risk and Depressive Symptoms: A Causal Mediation Analysis of the ADNI Cohort

article en

Abstract

This study aims to determine whether cerebral white matter hyperintensities (a marker of cerebral small vessel disease) mediate the relationship between cumulative vascular risk and the severity of depressive symptoms in an older adult population.

Open Science Framework
Good health and well-being
Openalex Percentile: Top 51%
Dementia and Cognitive Impairment Research
DOIOpen Access PDFOpenAlex
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The Mediating Role of White Matter Hyperintensities in the Association Between Vascular Risk and Depressive Symptoms: A Causal Mediation Analysis of the ADNI Cohort · Open Science Framework (2025) | TGRS Research Map | TGRS