MOLECULAR INSIGHTS INTO SYNERGISTIC AND COMPETITIVE INTERACTIONS OF PROBIOTIC STRAINS IN CACO-2 CO-CULTURE MODELS: A REVIEW

This systematic review explores the synergistic and competitive interactions of probiotic strains in Caco-2 co-culture models, focusing on their molecular impact on intestinal barrier integrity. A structured search will be conducted in PubMed, Scopus, Web of Science, and SciFinder, following PRISMA guidelines for study selection. The review will assess methodological quality using the Adapted SciRAP in vitro tool and categorize findings based on probiotic interactions, molecular mechanisms, and study variations. Bibliometric analysis (VOSviewer) will identify research trends and gaps.

Publication Details

Journal
Open Science Framework
Published
2025-01-01
DOI
https://doi.org/10.17605/osf.io/qvghm
Primary Topic
Probiotics and Fermented Foods
Type
article
Field-Weighted Citation Impact
0.00
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article

MOLECULAR INSIGHTS INTO SYNERGISTIC AND COMPETITIVE INTERACTIONS OF PROBIOTIC STRAINS IN CACO-2 CO-CULTURE MODELS: A REVIEW

Open Science Framework
Probiotics and Fermented Foods
article

MOLECULAR INSIGHTS INTO SYNERGISTIC AND COMPETITIVE INTERACTIONS OF PROBIOTIC STRAINS IN CACO-2 CO-CULTURE MODELS: A REVIEW

article en

Abstract

This systematic review explores the synergistic and competitive interactions of probiotic strains in Caco-2 co-culture models, focusing on their molecular impact on intestinal barrier integrity. A structured search will be conducted in PubMed, Scopus, Web of Science, and SciFinder, following PRISMA guidelines for study selection. The review will assess methodological quality using the Adapted SciRAP in vitro tool and categorize findings based on probiotic interactions, molecular mechanisms, and study variations. Bibliometric analysis (VOSviewer) will identify research trends and gaps.

Open Science Framework
Openalex Percentile: Top 53%
Probiotics and Fermented Foods
DOIOpen Access PDFOpenAlex
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MOLECULAR INSIGHTS INTO SYNERGISTIC AND COMPETITIVE INTERACTIONS OF PROBIOTIC STRAINS IN CACO-2 CO-CULTURE MODELS: A REVIEW · Open Science Framework (2025) | TGRS Research Map | TGRS