Pharmacokinetic Modeling of Itraconazole and Terbinafine for Sporotrichosis Treatment: A Monte Carlo Simulation Approach

This project aims to evaluate the pharmacokinetics of itraconazole and terbinafine in sporotrichosis treatment through systematic review and Monte Carlo simulations. The goal is to optimize dosing regimens by analyzing parameters such as Cmax, AUC, and clearance. Data will be compiled from PubMed and Web of Science, and simulations will be performed using Crystal Ball or SPSS.

Publication Details

Journal
Open Science Framework
Published
2025-01-01
DOI
https://doi.org/10.17605/osf.io/j8fzx
Primary Topic
Fungal Infections and Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Pharmacokinetic Modeling of Itraconazole and Terbinafine for Sporotrichosis Treatment: A Monte Carlo Simulation Approach

Open Science Framework
Fungal Infections and Studies
article

Pharmacokinetic Modeling of Itraconazole and Terbinafine for Sporotrichosis Treatment: A Monte Carlo Simulation Approach

article en

Abstract

This project aims to evaluate the pharmacokinetics of itraconazole and terbinafine in sporotrichosis treatment through systematic review and Monte Carlo simulations. The goal is to optimize dosing regimens by analyzing parameters such as Cmax, AUC, and clearance. Data will be compiled from PubMed and Web of Science, and simulations will be performed using Crystal Ball or SPSS.

Open Science Framework
Openalex Percentile: Top 47%
Fungal Infections and Studies
DOIOpen Access PDFOpenAlex
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Pharmacokinetic Modeling of Itraconazole and Terbinafine for Sporotrichosis Treatment: A Monte Carlo Simulation Approach · Open Science Framework (2025) | TGRS Research Map | TGRS