Advances of OTSC in managing anastomotic leak and fistulas after colorectal cancer surgery

Anastomotic leak (AL) is one of the severe complications following colorectal cancer surgery, significantly impacting the patient prognosis and potentially endangering their life. Current treatments for AL involve colostomy diversion surgery or long-term total parenteral nutrition with abdominal drainage, supplemented by other conservative measures. However, the overall effectiveness of these treatments remains unsatisfactory. In recent years, endoscopic techniques have emerged as a promising therapeutic option for the treatment of AL. Among these, a novel rake-shaped closure system, known as the over-the-scope clip (OTSC), has been recognized by clinicians for its simple operation, few complications, high technical success rate and high clinical success rate.