Correlation between methylation level of <i>TBKBP1</i> DMR and <i>TBKBP1</i> expression in CD8<sup>+</sup> T cells from CMV-seronegative donors.

<p><b>(A)</b> Mean methylation level of <i>TBKBP1</i> DMR in sorted CD8<sup>+</sup> T cell subsets T<sub>N</sub>, T<sub>SCM</sub>, T<sub>CM</sub>, T<sub>EM</sub>, and T<sub>EMRA</sub> cells from five CMV-seronegative donors are shown. <b>(B)</b> <i>TBKBP1</i> expression in indicated CD8<sup>+</sup> T cell subsets from five CMV-seronegative donors were analysed by RT-PCR. <b>(C)</b> Correlation analysis visualize the relation between methylation status of <i>TBKBP1</i> DMR (x-axis) and associated <i>TBKBP1</i> gene expression (y-axis) including the linear regression line and the Pearson correlation coefficient (r).</p> <p>(PDF)</p>

Publication Details

Journal
Figshare
Published
2024-09-26
DOI
https://doi.org/10.1371/journal.ppat.1012581.s003
Primary Topic
Immunodeficiency and Autoimmune Disorders
Type
article
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article

Correlation between methylation level of TBKBP1 DMR and TBKBP1 expression in CD8+ T cells from CMV-seronegative donors.

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Immunodeficiency and Autoimmune Disorders
article

Correlation between methylation level of TBKBP1 DMR and TBKBP1 expression in CD8+ T cells from CMV-seronegative donors.

article en

Abstract

<p><b>(A)</b> Mean methylation level of <i>TBKBP1</i> DMR in sorted CD8<sup>+</sup> T cell subsets T<sub>N</sub>, T<sub>SCM</sub>, T<sub>CM</sub>, T<sub>EM</sub>, and T<sub>EMRA</sub> cells from five CMV-seronegative donors are shown. <b>(B)</b> <i>TBKBP1</i> expression in indicated CD8<sup>+</sup> T cell subsets from five CMV-seronegative donors were analysed by RT-PCR. <b>(C)</b> Correlation analysis visualize the relation between methylation status of <i>TBKBP1</i> DMR (x-axis) and associated <i>TBKBP1</i> gene expression (y-axis) including the linear regression line and the Pearson correlation coefficient (r).</p> <p>(PDF)</p>

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Immunodeficiency and Autoimmune Disorders
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