<i>F</i>. <i>oxysporum</i> Mac1 directly activates transcription of copper deficiency response genes.

<p><b>(A)</b> Putative consensus DNA sequence bound by <i>F</i>. <i>oxysporum</i> Mac1, identified by exporting the genomic sequences around the peak locations (500 bp) of Mac1 binding sites obtained by ChIP-seq and submitting them to BLASTn analysis. Within these regions the consensus sequence TGCTCA was identified. <b>(B-G).</b> Abundance of RNA-seq transcript reads of the wt (dark blue) or the <i>mac1</i>Δ strain (red) under -Cu conditions (RNA-seq, upper graphs); or of gDNA reads from ChIP-seq analysis in the <i>mac1</i><sup>Stag</sup> strain under -Cu (grey) or +Cu (light blue) conditions (ChIP-seq, lower graphs). Data are represented as base-level coverage to three <i>Fol4287</i> gene clusters <b>(B-D)</b> or genes <b>(E-G)</b>. Genes are indicated as red boxes and putative Mac1 binding sites on each strand by black triangles.</p> <p>(PDF)</p>