Antiviral activity of the natural compounds.

<p>The MTT-based cell viability assay was performed using 85 compounds (derived from herbs used in traditional home medicine systems) and 66 compounds were selected that were not toxic at 0.5 to 1 μM concentration using human breast cancer (MCF7) and bone cancer (U2OS) cells, both possessing wild type p53 (similar to the normal cells). All compounds were procured in their purified form (95% purity) from commercial suppliers such as Sigma, Wako and Tokiwa phytochemicals, Japan. The table above shows the anti-CHIKV activity of those 66 compounds in ERMS and BHK-21 cells.</p> <p>(DOCX)</p>