Anti-oncogenic activity of novel compounds and reference drugs <i>in vitro</i>. IGROV1 cells were treated with a series of FLT3/TAF1 compounds and cell viability was determined using a CellTiter Glo assay.

Dose response curves were generated in triplicate, and each dose-response curve represents an independent experiment. Dots represent individual data points, and the gray area represents the 95% confidence interval for each curve. Both single FLT3 inhibitors (3i-1244, 3i-1245, 3i-1247) and dual FLT3/TAF1 inhibitors (3i-1103, 3i-1246, 3i-1248) were used for experiments. (PDF)

Publication Details

Journal
Figshare
Published
2025-03-28
DOI
https://doi.org/10.1371/journal.pone.0320443.s007
Primary Topic
Cell death mechanisms and regulation
Type
article
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article

Anti-oncogenic activity of novel compounds and reference drugs in vitro. IGROV1 cells were treated with a series of FLT3/TAF1 compounds and cell viability was determined using a CellTiter Glo assay.

Figshare
Cell death mechanisms and regulation
article

Anti-oncogenic activity of novel compounds and reference drugs in vitro. IGROV1 cells were treated with a series of FLT3/TAF1 compounds and cell viability was determined using a CellTiter Glo assay.

article en

Abstract

Dose response curves were generated in triplicate, and each dose-response curve represents an independent experiment. Dots represent individual data points, and the gray area represents the 95% confidence interval for each curve. Both single FLT3 inhibitors (3i-1244, 3i-1245, 3i-1247) and dual FLT3/TAF1 inhibitors (3i-1103, 3i-1246, 3i-1248) were used for experiments. (PDF)

Figshare
Openalex Percentile: Top 62%
Cell death mechanisms and regulation
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Anti-oncogenic activity of novel compounds and reference drugs <i>in vitro</i>. IGROV1 cells were treated with a series of FLT3/TAF1 compounds and cell viability was determined using a CellTiter Glo assay. · Figshare (2025) | TGRS Research Map | TGRS