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Supporting data: Table S1. Data for Figure 2 MTT assay. Table S2. Data analysis results for Figure 2. Ordinary one-way ANOVA with post-hoc Tukey test. Table S3. Data for Figure S1A THP-1 monocytes control. Table S4. Data for Figure S1B Standard curve example. Table S5. Data for Figure S1C Sample dilution optimization. Table S6. Data for Figure 3 IL-1β stimulation. Table S7. Data analysis results for Figure 3 at 6h of treatment. Ordinary one-way ANOVA with post-hoc Tukey test. Table S8. Data analysis results for Figure 3 at 24h of treatment. Ordinary one-way ANOVA with post-hoc Tukey test. Table S9. Data analysis results for Figure 3 at 48h of treatment. Ordinary one-way ANOVA with post-hoc Tukey test. Table S10. Data analysis results for Figure 3 at 72h of treatment. Ordinary one-way ANOVA with post-hoc Tukey test. Table S11. Data analysis results for Figure 3 for media treatment. Kluskal-Wallis test with post-hoc Dunn’s test. Table S12. Data analysis results for Figure 3 for 1 ng/ml IL-1β treatment. Kluskal-Wallis test with post-hoc Dunn’s test. Table S13. Data analysis results for Figure 3 for 10 ng/ml IL-1β treatment. Kluskal-Wallis test with post-hoc Dunn’s test. Table S14. Data analysis results for Figure 3 for 100 ng/ml IL-1β treatment. Kluskal-Wallis test with post-hoc Dunn’s test. Table S15. Data for Figure S2A at 6h of treatment. Table S16. Data analysis results for Figure S2A at 6h of treatment. Ordinary one-way ANOVA with post-hoc Tukey test. Table S17. Data for Figure S2B at 24h of treatment. Table S18. Data analysis results for Figure S2B at 24h of treatment. Ordinary one-way ANOVA with post-hoc Tukey test. Table S19. Data for Figure S2C at 48h of treatment. Table S20. Data analysis results for Figure S2C at 48h of treatment. Ordinary one-way ANOVA with post-hoc Tukey test. Table S21. Data for Figure S2D at 72h of treatment. Table S22. Data analysis results for Figure S2D at 72h of treatment. Ordinary one-way ANOVA with post-hoc Tukey test. Table S23. Data for Figure S3A for media treatment. Table S24. Data analysis results for Figure S3A for media treatment. Kluskal-Wallis test with post-hoc Dunn’s test. Table S25. Data for Figure S3B for 1 ng/ml IL-1β treatment. Table S26. Data analysis results for Figure S3B for 1 ng/ml IL-1β treatment. Kluskal-Wallis test with post-hoc Dunn’s test. Table S27. Data for Figure S3C for 10 ng/ml IL-1β treatment. Table S28. Data analysis results for Figure S3C for 10 ng/ml IL-1β treatment. Kluskal-Wallis test with post-hoc Dunn’s test. Table S29. Data for Figure S3D for 100 ng/ml IL-1β treatment. Table S30. Data analysis results for Figure S3D for 100 ng/ml IL-1β treatment. Kluskal-Wallis test with post-hoc Dunn’s test. Table S31. Data for Figure 4 MTT assay. Table S32. Data analysis results for Figure 4. Kluskal-Wallis test with post-hoc Dunn’s test. Table S33. Data for Figure 5A for pre-treatment with canakinumab. Table S34. Data analysis results for Figure 5A for pre-treatment with canakinumab. Ordinary one-way ANOVA with post-hoc Tukey test. Table S35. Data for Figure 5A for co-incubation of canakinumab and IL-1β. Table S36. Data analysis results for Figure 5A for co-incubation of canakinumab and IL-1β. Ordinary one-way ANOVA with post-hoc Tukey test. Table S37. Data used for Figure 5B for pre-treatment with canakinumab. Analysis of Inhibition dose-response using a non-linear regression model to calculate IC50, per treatment time point. Table S38. Data used for Figure 5B for co-incubation of canakinumab and IL-1β. Analysis of Inhibition dose-response using a non-linear regression model to calculate IC50, per treatment time point. Table S39. Data for Figure 6 MTT assay. Table S40. Data analysis results for Figure 6. Ordinary one-way ANOVA with post-hoc Dunnett’s multiple comparisons test. Table S41. Data for Figure 7A myoblasts. Table S42. Data analysis results for Figure 7A. Ordinary one-way ANOVA with post-hoc Tukey test. Table S43. Data for Figure 7B myotubes. Table S44. Data analysis results for Figure 7B. Ordinary one-way ANOVA with post-hoc Tukey test. (PDF)