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S1 Table. Demographics/Population characteristics. Abbreviations here and below: Czech Republic (CZ), Germany (DE), Spain (ES), France (FR), Greece (GR), Hungary (HU), Italy (IT), Netherlands (NL), Poland (PL), Romania (RO), Sweden (SE), Turkey (TR), United Kingdom (UK). S2 Table. Criteria for excluding survey data from statistical and/or textual analysis. S3 Table. Sample size per country before and after removing invalid entries. S4 Table. Mean acceptability of SC-based applications. Anticancer therapy (V1), Conversion of CO2 emissions to biofuel (V2) and Industrial waste recycling (V3). S5 Table. Synthetic cell applications acceptance per gender: Mean and Standard Deviation. Synthetic cell applications acceptance per gender: Mean and Standard Deviation. S6 Table. Synthetic cell applications acceptance per age category: Mean and Standard Deviation. S7 Table. Synthetic cell applications acceptance per education level: Mean and Standard Deviation. S8 Table. Synthetic cell applications acceptance per religion: Mean and Standard Deviation. S9 Table. Synthetic cell applications acceptance per country: Mean and Standard Deviation. S10 Table. Topic modeling of the respondents’ comments to scenario 1 (anticancer therapy). The “topic” column contains a “label” description reflecting the author’s interpretation of the topic as based on the top words and confirmed by typical entries per topic. Weight indicates relative prominence of the topics within the model (numeric values depend on the number of iterations). LL/T (log-likelihood per token) represents the overall model fit. S11 Table. Topic modeling of the respondents’ comments to scenario 2 (conversion of CO2 emissions to biofuel). The “topic” column contains a description reflecting the author’s interpretation of the topic as based on the top words and confirmed by typical entries per topic. Weight indicates relative prominence of the topics within the model (numeric values depend on the number of iterations). LL/T (log-likelihood per token) represents the overall model fit. S12 Table. Topic modeling of the respondents’ comments to scenario 3 (industrial waste recycling). The “topic” column contains a description reflecting the author’s interpretation of the topic as based on the top words and confirmed by typical entries per topic. Weight indicates relative prominence of the topics within the model (numeric values depend on the number of iterations). LL/T (log-likelihood per token) represents the overall model fit. S1 Fig. Mean acceptability of SC-based applications. Anticancer therapy (V1), Conversion of CO2 emissions to biofuel (V2), and Industrial waste recycling (V3). S2 Fig. Perceived acceptability of SC-based applications per gender. S3 Fig . Perceived acceptability of SC-based applications per age. S4 Fig . Perceived acceptability of SC-based applications per education level. S5 Fig . Perceived acceptability of SC-based applications per religion. S6 Fig . Perceived acceptability of SC-based anticancer therapy (scenario 1) per country. S7 Fig. Perceived acceptability of SC-based conversion of CO2 emissions to biofuel (scenario 2) per country. S8 Fig. Perceived acceptability of SC-based industrial waste recycling (scenario 3) per country. S9 Fig. Perceived acceptability of SC-based applications: Decision Tree. Bars in the boxes show Likert scale score distribution. S10 Fig. Perceived willingness to use SC-based applications: Decision Tree. Bars in the boxes show Likert scale score distribution. S11 Fig . Topic modeling process overview. S12 Fig. Visualization of integrated TM and SA: SC anticancer therapy scenario. The centrality of the box and the intensity of yellow reflect topic weight (prominence) vs. other topics. Word size represents relative frequency of the words within the topic. Additionally, word colors indicate sentiment: green for positive, red for negative, and blue for neutral. S13 Fig. Visualization of integrated TM and SA: SC-based conversion of CO2 emissions to biofuel. The centrality of the box and the intensity of yellow reflect topic weight (prominence) vs. other topics. Word size represents relative frequency of the words within the topic. Additionally, word colors indicate sentiment: green for positive, red for negative, and blue for neutral. S14 Fig. Visualization of integrated TM and SA: CS-based industrial waste recycling scenario. The centrality of the box and the intensity of yellow reflect topic weight (prominence) vs. other topics. Word size represents relative frequency of the words within the topic. Additionally, word colors indicate sentiment: green for positive, red for negative, and blue for neutral. (PDF)

Publication Details

Journal
Figshare
Published
2025-02-27
DOI
https://doi.org/10.1371/journal.pone.0319337.s001
Primary Topic
Biomedical Ethics and Regulation
Type
article
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Biomedical Ethics and Regulation
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Abstract

S1 Table. Demographics/Population characteristics. Abbreviations here and below: Czech Republic (CZ), Germany (DE), Spain (ES), France (FR), Greece (GR), Hungary (HU), Italy (IT), Netherlands (NL), Poland (PL), Romania (RO), Sweden (SE), Turkey (TR), United Kingdom (UK). S2 Table. Criteria for excluding survey data from statistical and/or textual analysis. S3 Table. Sample size per country before and after removing invalid entries. S4 Table. Mean acceptability of SC-based applications. Anticancer therapy (V1), Conversion of CO2 emissions to biofuel (V2) and Industrial waste recycling (V3). S5 Table. Synthetic cell applications acceptance per gender: Mean and Standard Deviation. Synthetic cell applications acceptance per gender: Mean and Standard Deviation. S6 Table. Synthetic cell applications acceptance per age category: Mean and Standard Deviation. S7 Table. Synthetic cell applications acceptance per education level: Mean and Standard Deviation. S8 Table. Synthetic cell applications acceptance per religion: Mean and Standard Deviation. S9 Table. Synthetic cell applications acceptance per country: Mean and Standard Deviation. S10 Table. Topic modeling of the respondents’ comments to scenario 1 (anticancer therapy). The “topic” column contains a “label” description reflecting the author’s interpretation of the topic as based on the top words and confirmed by typical entries per topic. Weight indicates relative prominence of the topics within the model (numeric values depend on the number of iterations). LL/T (log-likelihood per token) represents the overall model fit. S11 Table. Topic modeling of the respondents’ comments to scenario 2 (conversion of CO2 emissions to biofuel). The “topic” column contains a description reflecting the author’s interpretation of the topic as based on the top words and confirmed by typical entries per topic. Weight indicates relative prominence of the topics within the model (numeric values depend on the number of iterations). LL/T (log-likelihood per token) represents the overall model fit. S12 Table. Topic modeling of the respondents’ comments to scenario 3 (industrial waste recycling). The “topic” column contains a description reflecting the author’s interpretation of the topic as based on the top words and confirmed by typical entries per topic. Weight indicates relative prominence of the topics within the model (numeric values depend on the number of iterations). LL/T (log-likelihood per token) represents the overall model fit. S1 Fig. Mean acceptability of SC-based applications. Anticancer therapy (V1), Conversion of CO2 emissions to biofuel (V2), and Industrial waste recycling (V3). S2 Fig. Perceived acceptability of SC-based applications per gender. S3 Fig . Perceived acceptability of SC-based applications per age. S4 Fig . Perceived acceptability of SC-based applications per education level. S5 Fig . Perceived acceptability of SC-based applications per religion. S6 Fig . Perceived acceptability of SC-based anticancer therapy (scenario 1) per country. S7 Fig. Perceived acceptability of SC-based conversion of CO2 emissions to biofuel (scenario 2) per country. S8 Fig. Perceived acceptability of SC-based industrial waste recycling (scenario 3) per country. S9 Fig. Perceived acceptability of SC-based applications: Decision Tree. Bars in the boxes show Likert scale score distribution. S10 Fig. Perceived willingness to use SC-based applications: Decision Tree. Bars in the boxes show Likert scale score distribution. S11 Fig . Topic modeling process overview. S12 Fig. Visualization of integrated TM and SA: SC anticancer therapy scenario. The centrality of the box and the intensity of yellow reflect topic weight (prominence) vs. other topics. Word size represents relative frequency of the words within the topic. Additionally, word colors indicate sentiment: green for positive, red for negative, and blue for neutral. S13 Fig. Visualization of integrated TM and SA: SC-based conversion of CO2 emissions to biofuel. The centrality of the box and the intensity of yellow reflect topic weight (prominence) vs. other topics. Word size represents relative frequency of the words within the topic. Additionally, word colors indicate sentiment: green for positive, red for negative, and blue for neutral. S14 Fig. Visualization of integrated TM and SA: CS-based industrial waste recycling scenario. The centrality of the box and the intensity of yellow reflect topic weight (prominence) vs. other topics. Word size represents relative frequency of the words within the topic. Additionally, word colors indicate sentiment: green for positive, red for negative, and blue for neutral. (PDF)

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Biomedical Ethics and Regulation
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