UPF1 sequence comparison.

Residues that are involved in UPF2 interaction in the human protein (PMID: 19556969) are indicated (green boxes below the alignment). Residues engaging in ATP binding have purple boxes. The DEAD-box helicase motif of UPF1 is highlighted. (Hs, <i>Homo sapiens</i> (Q92900); Ce, <i>Caenorhabditis elegans</i> (O76512); Dm, <i>Drosophila melanogaster</i> (Q9VYS3); Eg, <i>Euglena gracilis</i> (EG_transcript_1144); Sc, <i>Saccharomyces cerevisiae</i> (P30771); Tb, <i>Trypanosoma brucei</i> (Tb927.5.2140); Tc, <i>Trypanosoma cruzi</i> (C3747_24g302). (PDF)