β-hematin inhibition assay for quinoxaline analogs and antimalarial control compounds.
Representative plot showing inhibition of β-hematin formation versus concentration profiles for MMV007224 (black), MMV665794 (red), chloroquine (blue) and KAE609 (green). Adjacent IC<sub>50</sub> data represent mean values of two biological replicates performed with technical duplicates. Data were fitted to the sigmoidal concentration response (variable slope) equation in GraphPad Prism to determine the IC<sub>50</sub>. (PDF)
Publication Details
- Journal
- Figshare
- Published
- 2025-02-03
- DOI
- https://doi.org/10.1371/journal.ppat.1012216.s007
- Primary Topic
- Synthesis and Biological Evaluation
- Type
- article
- Field-Weighted Citation Impact
- 0.00