FBP plays a crucial role in inhibiting viral infection.

<p>(A and B) RAW264.7 cells were transfected with siControl (siCtrl), pan-siHMGB or siHMGB2, treated with 5 mM FBP for 12 h and infected with VSV (MOI, 0.1) for 10 h. Then, the expression of HMGB1 and HMGB2 was analyzed by western blot and qPCR (A). The RNA levels of VSV were assessed by qPCR (B). Data are presented as the mean ± SEM. NS, not significant, *<i>p</i> < 0.05; **<i>p</i> < 0.01. In (B), statistical analyses were performed with one-way ANOVA. In right panels of (A), statistical analyses were performed with two-tailed Student’s t test.</p> <p>(DOCX)</p>