Hazard ratios between cancer-specific polygenic risk scores and other cancer outcomes.

HRs were estimated using a Cox regression model adjusted for age, sex (if applicable), region, and the top 10 principal components (left) and they were further adjusted for the corresponding site-specific PRSs (right). The significance levels in the figure are denoted by asterisks as follows: * <i>P</i>-value < 0.05, **<i>P</i>-value < 0.01, and ***<i>P</i>-value < 0.001. PRS, polygenic risk score; HR, hazard ratio. (DOCX)

Publication Details

Journal
Figshare
Published
2025-02-28
DOI
https://doi.org/10.1371/journal.pmed.1004534.s032
Primary Topic
Inflammatory Biomarkers in Disease Prognosis
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article
Field-Weighted Citation Impact
0.00
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Hazard ratios between cancer-specific polygenic risk scores and other cancer outcomes.

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Inflammatory Biomarkers in Disease Prognosis
article

Hazard ratios between cancer-specific polygenic risk scores and other cancer outcomes.

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Abstract

HRs were estimated using a Cox regression model adjusted for age, sex (if applicable), region, and the top 10 principal components (left) and they were further adjusted for the corresponding site-specific PRSs (right). The significance levels in the figure are denoted by asterisks as follows: * <i>P</i>-value < 0.05, **<i>P</i>-value < 0.01, and ***<i>P</i>-value < 0.001. PRS, polygenic risk score; HR, hazard ratio. (DOCX)

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Inflammatory Biomarkers in Disease Prognosis
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Hazard ratios between cancer-specific polygenic risk scores and other cancer outcomes. · Figshare (2025) | TGRS Research Map | TGRS