Summary results of TWAS fine-mapping in UK Biobank (FABIO input options for <i>π</i>).
<p>The table summarizes the number of discoveries for each of the six disease traits (rows) in the TWAS fine-mapping analysis of UK Biobank. A risk region with GWAS or TWAS signals (1<sup>st</sup> column) is defined as an LD block that harbors at least one genome-wide significant SNP or significant TWAS gene same as the definition we applied in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011503#pgen.1011503.t001" target="_blank">Table 1</a> of the main text. The following two columns list the number of genes discovered by applying FABIO with default prior and beta prior on <i>π</i>, respectively. The number in the bracket is the number of identified genes that are located in a risk region with GWAS or TWAS signals. We used an estimated FDR threshold of 0.05 to declare significance in the fine-mapping analysis.</p> <p>(DOCX)</p>
Publication Details
- Journal
- Figshare
- Published
- 2024-12-02
- DOI
- https://doi.org/10.1371/journal.pgen.1011503.s001
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00