Characterization of epithelial stem cell engulfment of apoptotic extracellular vesicles.

<p>(A) Two ROIs of 2 epithelial stem cells engulfing apoptotic cells. (B) The number of engulfment events over a 23-h timeframe. (C) Representative images of the levels of NTR positive cells up to 24 hpt. (D) Quantification of the number of dying cells over time after MTZ treatment. <i>n</i> = 3, 0 hpt; <i>n</i> = 4, 8 hpt; <i>n</i> = 3, 18 hpt; <i>n</i> = 4, 24 hpt. Adjusted <i>p</i>-values: ** 0.0058, 0 hpt vs. 18 hpt; ** 0.0042, 0 hpt vs. 24 hpt; * 0.0404, 8 hpt vs. 18 hpt; *0.0308, 8 hpt vs. 24 hpt via a one-way ANOVA using a Tukey’s ad hoc test. The underlying data for the graphs in this figure can be found in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002194#pbio.3002194.s017" target="_blank">S2 Data</a>.</p> <p>(PDF)</p>