Comparative analysis of cerebral circulation impairment in humans and horses: Implications for veterinary and human medicine

\nThe comparison of cerebral circulation impairment in humans and horses provides important insights into the dynamics of blood flow in the brain across different species, connecting veterinary and human medicine. This analysis brings together findings from various studies to highlight the similarities in anatomy and physiology between humans and horses, which can improve our understanding of cerebrovascular health. Research emphasizes the importance of maintaining stable cerebral blood flow to prevent damage from lack of oxygen, which is essential for the brain’s metabolism in both humans and horses. Studies on the factors affecting overall blood flow in the body reveal strong connections between cardiovascular health and blood flow to the brain, showing how baroreflex sensitivity and blood pressure play a role in maintaining brain function. Understanding the reactivity of blood vessels in the brain is associated with neurological disorders, emphasizing the need for non-invasive evaluation techniques that can be used for both humans and horses. Research on the coupling of nerve and blood vessel activity further explains how blood flow is regulated during brain activity, highlighting potential weaknesses under unhealthy conditions. While the role of exercise in promoting cerebrovascular health is recognized, there are still gaps in our knowledge of its effects on the brain, especially in horses. Advanced imaging techniques like MRI are presented as essential tools for assessing the health of small blood vessels and blood flow in the brain, offering potential applications in the early detection and treatment of cerebrovascular diseases. By comparing the dynamics of blood flow in the brain in humans and horses, this review not only increases our understanding but also suggests a more integrated approach to diagnosis and treatment, improving practices in both fields. These insights emphasize the common principles and specific differences in cerebrovascular health in different species, and support the need for collaborative research in veterinary and human medicine.\n