Natural\nProtein-Based Biogels with Biomimetic Mechanics\nand Multifunctionality for Skin Sensors

Developing\nskin-like ionic sensing materials is highly\ndesirable\nfor skin bioelectronics for long-term health monitoring, which is\nchallenging to realize by using biocompatible natural polymer-based\nbiogels. Herein, we engineer a robust natural protein-based ionic\nbiogel with skin-like combinational properties involving stretchability,\nsoftness, durability, ionic conductivity, and environmental adaptability,\nwhich is enabled by a synergistic effect of biomimetic nanofibrous\nstructures as well as solvent and ionic enhancement. The skin-like\nmechanics and functionality of the as-designed natural protein-based\nbiogels suggest their further applications in advanced skin sensors\nfor long-term and high-fidelity physiological monitoring. As a proof\nof concept, we successfully demonstrate high-quality continuous monitoring\nof electrocardiograms for 1 week under daily life conditions using\nsuch natural protein-based skin-like ionic biogels.