Ag-Doped SnSe Nanosheets\nfor Enhanced NIR-II Light-Induced\nApoptosis

Triple-negative breast cancer (TNBC) is one of the most\naggressive\nand challenging subtypes with limited treatment options and poor prognosis.\nTo overcome these obstacles, Ag-doped SnSe (ASS) nanosheets were used\nas photonic hyperthermia agents for treating TNBC. ASS featured a\nhigh photothermal-conversion efficiency and photon hyperthermia effect.\nAdditionally, biosafety assessments, including hemolysis assays and\nhistopathological analysis, confirmed that ASS was biosafety. These\nfindings suggest that ASS, in synergy with the second near-infrared\nbiowindow (NIR-II) light irradiation, offers a noninvasive, effective,\nand safe therapeutic strategy for TNBC. This innovative approach exemplifies\nthe evolving landscape of TNBC treatment, where technology and biology\nconverge to offer more precise and personalized therapies.