Electrochemical\nFerrier Rearrangement of Glycals

The\nFerrier rearrangement (FR) is a well-documented reaction\nthat\nrelies on strong acids or oxidants to convert glycals into unsaturated\nglycosyl derivatives. In this work, we introduce an electrochemical\nvariant of the FR, offering a broad substrate compatibility. Various\nnucleophiles and glycal derivatives afford 2,3-unsaturated glycosyl\nderivatives in high yields with excellent diastereoselectivities.\nThis sustainable method promises to expand the electrochemistry applications\nin sugar chemistry.