β‑Thioamide\nSulfone Enabled Copper-Catalyzed\nRing-Opening/Sulfonylation of Cyclopropenes: Access to Alkyl Aryl\nSulfones

Sulfone motifs play important roles in bioactive compounds\nand\nfunctional materials. The development of efficient methodologies for\nconstructing sulfonyl-containing compounds has thus attracted considerable\nattention. Here, we introduce a protocol for the preparation of alkyl\naryl sulfones under mild conditions. This protocol employs β-thioamide\nsulfone as a novel sulfone motif donor. It forms sulfinates in situ\nunder basic conditions, which then undergo cross-coupling with the\nintermediates that were generated from ligand-free copper-catalyzed\ncyclopropenes (CPEs) ring opening.