Gold(I)-Catalyzed\n6-<i>exo</i>-<i>dig</i> Hydroamination/7-<i>endo</i>-<i>dig</i> Cycloisomerization\nDomino Approach to 3,7<i>a</i>‑Diazacyclohepta[<i>jk</i>]fluorene Derivativ

A series\nof 3,7<i>a</i>-diazacyclohepta[<i>jk</i>]fluorene\nderivatives were synthesized via a gold(I)-catalyzed 6-<i>exo</i>-<i>dig</i> hydroamination/7-<i>endo</i>-<i>dig</i> cycloisomerization domino method. The method\nexhibits a broad substrate scope, and a plausible mechanism has been\nproposed. The efficacy of this\nstrategy is further validated by the successful derivatization of\n3,7<i>a</i>-diazacyclohepta[<i>jk</i>]fluorene.