Synthesis of Sulfinamidines\nvia Iron-Catalyzed Nitrene\nTransfer Reaction with Sulfenamides

An iron-catalyzed nitrene transfer reaction for the rapid\nsynthesis\nof sulfinamidines from readily available sulfenamides is reported.\nThis method features mild conditions, short reaction times, and a\nbroad substrate scope, allowing the preparation of a variety of sulfinamidines\nin good to excellent yields. The synthetic utility of the sulfinamidine\nproducts was further demonstrated through their conversion to other\nvaluable sulfur(VI) compounds, such as sulfondiimidoyl fluorides,\nsulfinamidiate esters, and sulfonimidamides. Preliminary efforts in\nthe development of an asymmetric variant showed moderate enantioselectivity.