Reagent-Free Intramolecular\nHydroamination of Ynone-Tethered\nAryl-sulfonamide: Synthesis of Polysubstituted 4‑Quinolones

An efficient reagent-free method for the synthesis of\npolysubstituted\n4-quinolone from 2-substituted alkynoyl aryl-sulfonamide was developed.\nThis developed method tolerates various functional groups and gives\nthe corresponding 4-quinolones. We have successfully extended this\nmethod to the synthesis of dihydro-4-quinolones from 2-alkenoyl aryl\nsulfonamide derivatives.