Versatile MXenzymes\nScavenging ROS for Promotion of\nSeed Germination under Salt Stress

Salinization is recognized as a global\nproblem, restricting\nagricultural\nproduction and sustainability. Targeting the salinity-induced oxidative\nstress, antioxidant treatment represents a protective strategy to\nimprove plant salt tolerance. Herein, we report a V<sub>4</sub>C<sub>3</sub> MXene nanozyme (MXenzyme), which exhibits good biocompatibility\nand excellent reactive oxygen species scavenging activity to ameliorate\nthe salt stress-induced inhibition of seed germination. V<sub>4</sub>C<sub>3</sub> MXenzyme treatment can significantly relieve salinity-induced\noxidative stress and restore the antioxidant system in pea seeds,\nthus improving the phenotypic traits during germination. The molecular\nmechanism by which antioxidant V<sub>4</sub>C<sub>3</sub> MXenzymes\naugment salt tolerances is revealed through transcriptomics and metabolomics.\nV<sub>4</sub>C<sub>3</sub> MXenzymes significantly regulate the gene\nexpression of antioxidant enzymes and molecule biosynthesis that correlate\nclosely with hormone signal transduction genes and energy metabolism\ngenes. With correlation and the combined analysis, redox homeostasis\ntargeted by antioxidant V<sub>4</sub>C<sub>3</sub> MXenzymes plays\na critical role in promoting plant growth under salt stress.