Luminescent Metal–Organic Framework-Based Fluorescent\nSensor Array for Screening and Discrimination of Bisphenols

Extensive applications of bisphenols\nin industrial products have\nled to their release into aquatic environments, causing a great threat\nto human health due to their endocrine-disrupting effects, whereas\nexisting methods are difficult to implement the rapid and high-throughput\ndetection of multiple bisphenols. To circumvent this issue, we constructed\na sensor array using two luminescent metal–organic frameworks\n(LMOFs) (Zr-BUT-12 and Ga-MIL-61) for the rapid discrimination of\nsix bisphenol contaminants (BPA, BPS, BPB, BPF, BPAF, and TBBPA).\nWherein, Zr-BUT-12 and Ga-MIL-61 exhibited different fluorescence-emission\nproperties and good luminescent stability. Interestingly, bisphenols\nwith different structures had diverse quenching effects on the fluorescence\nintensity of Zr-BUT-12 and Ga-MIL-61 via the adsorptive interaction,\nresulting in unique fluorescent fingerprints. Based on pattern recognition\nmethods, different bisphenols were successfully identified, with the\nlimit of detection in the range of 1.59–16.7 ng/mL for six\nbisphenols. More importantly, the developed sensor array could be\neffectively utilized for distinguishing different ratios of mixed\nbisphenols, which was further applied for bisphenol discrimination\nin real water samples. Consequently, our finding provides a promising\nstrategy for the simultaneous recognition of multiple bisphenols,\nwhich encourages the development of a sensor array for the detection\nof multiple contaminants in environmental monitoring and food safety.