Photoactivatable mRNA 5′ Cap Analogs for RNA‐Protein Crosslinking (Adv. Sci. 36/2024)

mRNA CAp photoAffiNity LAbeLiNg pRobesChemically modified messenger RNA (mRNA) has been demonstrated to be a valuable therapeutic platform for antiviral vaccines.However, a more comprehensive understanding of its translation mechanisms is essential for the development of more effective therapeutics.The cover image depicts a translation initiation factor 4E in complex with an mRNA 5' cap structure, which was modified by Marcin Warminski and co-workers to create novel molecular tools for the identification of binders of different mRNA 5'-end variants.More details can be found in article number 2400994.

Publication Details

Journal
Advanced Science
Published
2024-09-01
DOI
https://doi.org/10.1002/advs.202470219
Primary Topic
Click Chemistry and Applications
Type
article
Field-Weighted Citation Impact
0.00
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article

Photoactivatable mRNA 5′ Cap Analogs for RNA‐Protein Crosslinking (Adv. Sci. 36/2024)

Advanced Science
Click Chemistry and Applications
article

Photoactivatable mRNA 5′ Cap Analogs for RNA‐Protein Crosslinking (Adv. Sci. 36/2024)

article en

Abstract

mRNA CAp photoAffiNity LAbeLiNg pRobesChemically modified messenger RNA (mRNA) has been demonstrated to be a valuable therapeutic platform for antiviral vaccines.However, a more comprehensive understanding of its translation mechanisms is essential for the development of more effective therapeutics.The cover image depicts a translation initiation factor 4E in complex with an mRNA 5' cap structure, which was modified by Marcin Warminski and co-workers to create novel molecular tools for the identification of binders of different mRNA 5'-end variants.More details can be found in article number 2400994.

Advanced ScienceVol. 11(36)
Good health and well-being
Openalex Percentile: Top 80%
Click Chemistry and Applications
DOIOpen Access PDFOpenAlex
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Photoactivatable mRNA 5′ Cap Analogs for RNA‐Protein Crosslinking (Adv. Sci. 36/2024) · Advanced Science (2024) | TGRS Research Map | TGRS