Combining glucagon-like peptide 1 analogues with sodium-glucose cotransporter 2 inhibitors to treat patients with type 1 diabetes, BMI > 25 kg/m2, and chronic kidney disease – A randomised, controlled pilot study
In patients with type 1 diabetes, BMI > 25 kg/m<sup>2</sup>, and chronic kidney disease, the combining GLP-1 + SGLT2i + lifestyle modification was safe and produced significant weight loss but did not significantly improve metabolic and blood pressure control.
Institutions
- University College Dublin (IE)
- Princess Nourah bint Abdulrahman University (SA)
- University of Ulster (GB)
- Amiri Hospital (KW)
- Dasman Diabetes Institute (KW)
- Imperial College London (GB)
Publication Details
- Journal
- Diabetes Research and Clinical Practice
- Published
- 2025-12-21
- DOI
- https://doi.org/10.1016/j.diabres.2025.113066
- Citations
- 1
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.29
Funders
- European Federation of Pharmaceutical Industries and Associations
- European Commission
- Princess Nourah Bint Abdulrahman University
- Dasman Diabetes Institute