Prevalence and associated factors of psychotic symptoms in young first-episode, drug-naïve major depressive disorder patients with abnormal lipid metabolism

Our study identified a high prevalence of psychotic symptoms in young MDD patients with ALM. Key predictors, including HAMD, HAMA, and TSH, demonstrated strong predictive accuracy. These findings highlight the potential of these factors for early identification of psychotic symptoms in this patient population. Future research is needed to validate these results and explore the underlying mechanisms.