Adjuvant Chemotherapy in Children With Enucleated Retinoblastoma and Histopathologic High-Risk Features: Survival Outcomes From a Single Institution in a Middle-Income Country

Histopathologic high-risk features are common among children undergoing enucleation for advanced retinoblastoma. Adjuvant chemotherapy is warranted in cases with massive choroidal invasion, scleral infiltration, or postlaminar optic nerve involvement, given their strong association with metastatic relapse.

Institutions

Publication Details

Journal
Cureus
Published
2025-12-21
DOI
https://doi.org/10.7759/cureus.99768
Primary Topic
Ocular Oncology and Treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Adjuvant Chemotherapy in Children With Enucleated Retinoblastoma and Histopathologic High-Risk Features: Survival Outcomes From a Single Institution in a Middle-Income Country

Cureus
Ocular Oncology and Treatments
article

Adjuvant Chemotherapy in Children With Enucleated Retinoblastoma and Histopathologic High-Risk Features: Survival Outcomes From a Single Institution in a Middle-Income Country

article en

Abstract

Histopathologic high-risk features are common among children undergoing enucleation for advanced retinoblastoma. Adjuvant chemotherapy is warranted in cases with massive choroidal invasion, scleral infiltration, or postlaminar optic nerve involvement, given their strong association with metastatic relapse.

CureusVol. 17(12)
Instituto Nacional de Cancerología (CO), Foscal Hospital (CO)
Openalex Percentile: Top 44%
Ocular Oncology and Treatments
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Adjuvant Chemotherapy in Children With Enucleated Retinoblastoma and Histopathologic High-Risk Features: Survival Outcomes From a Single Institution in a Middle-Income Country · Cureus (2025) | TGRS Research Map | TGRS