Clinical efficacy of amiodarone in prehospital emergency treatment of myocardial infarction: a systematic review and meta-analysis

This systematic review and meta-analysis demonstrated that prehospital amiodarone administration in patients with myocardial infarction significantly reduced the incidence of malignant arrhythmia and the average number of defibrillations, while improving the success rate of rescue. Furthermore, it lowered the incidence of adverse reactions, the recurrence rate of myocardial infarction, and shortened the length of hospital stay. These findings support the clinical promotion of amiodarone in prehospital emergency care for myocardial infarction.

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Publication Details

Journal
Journal of Cardiothoracic Surgery
Published
2025-12-21
DOI
https://doi.org/10.1186/s13019-025-03773-4
Primary Topic
Cardiac Arrest and Resuscitation
Type
article
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article

Clinical efficacy of amiodarone in prehospital emergency treatment of myocardial infarction: a systematic review and meta-analysis

Journal of Cardiothoracic Surgery
Cardiac Arrest and Resuscitation
article

Clinical efficacy of amiodarone in prehospital emergency treatment of myocardial infarction: a systematic review and meta-analysis

article en

Abstract

This systematic review and meta-analysis demonstrated that prehospital amiodarone administration in patients with myocardial infarction significantly reduced the incidence of malignant arrhythmia and the average number of defibrillations, while improving the success rate of rescue. Furthermore, it lowered the incidence of adverse reactions, the recurrence rate of myocardial infarction, and shortened the length of hospital stay. These findings support the clinical promotion of amiodarone in prehospital emergency care for myocardial infarction.

Journal of Cardiothoracic SurgeryVol. 21(1)
Zhejiang Chinese Medical University (CN), Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
Openalex Percentile: Top 43%
Cardiac Arrest and Resuscitation
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