Roles of KHDRBS2 and KHDRBS3 in prostate cancer progression and AR-V7 regulation
These findings uncover novel roles for KHDRBS2 and KHDRBS3 in PCa progression, with KHDRBS2 identified as a potential key regulator of AR-V7 expression. Our results provide new insights into AR splice variant regulation and highlight potential therapeutic targets for PCa treatment.
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Beijing Tian Tan Hospital (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-12-19
- DOI
- https://doi.org/10.1007/s12672-025-04294-1
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Tsinghua University
- Chinese Academy of Medical Sciences
- Peking Union Medical College