Response to a prehabilitation program for patients with oesophageal cancer: an observational study

On average, patients with oesophageal cancer improved in physical fitness and nutritional status during prehabilitation, recovering from the impact of neoadjuvant treatment. Response to prehabilitation was independent of baseline fitness. A greater decline in fitness during neoadjuvant treatment, lower fitness before prehabilitation and higher fatigue were associated with a positive response. The heterogeneity in preoperative trajectories among patients underscores the importance of regular monitoring to tailor interventions to individual needs.