Differential effects of admission glucose on outcomes in large ischemic stroke based on treatment modality and clinical characteristics: a prospective cohort study

Admission glucose exhibits differential impacts based on individual patient characteristics, revealing distinct glycemic susceptibility profiles. These findings demonstrate treatment-dependent glucose effects, with amplified adverse associations in EVT patients and those with high-susceptibility clinical features. Recognition of differential glycemic susceptibility provides mechanistic rationale for personalized glucose management strategies and supports precision medicine approaches in acute stroke.