No BCMA? No Problem: A CD70-Targeting CAR-NK Cell Shows Promise in High-risk Myeloma
Despite recent advances, multiple myeloma remains essentially incurable for most patients, particularly those with high-risk cytogenetics and those whose disease relapses after BCMA-targeting therapies. A novel CD27 CAR_sIL15 NK cell targeting CD70 may offer new hope in this area of urgent, unmet medical need. See related article by Lin et al., p. 234.
Institutions
- City of Hope (US)
- The Ohio State University (US)
Publication Details
- Journal
- Blood Cancer Discovery
- Published
- 2025-12-19
- DOI
- https://doi.org/10.1158/2643-3230.bcd-25-0394
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.00